Drug manufacture

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Tero
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Drug manufacture

Post by Tero » Mon Jan 08, 2018 2:57 am

Most drugs are invented and manufactured in Europe, USA and some developed countries in Asia plus Israel.

Russia has lagged behind and may not have full access to newest drugs. There was some illegal or against patent law manufacture until recent times.

https://gmpnews.net/2017/11/drug-import ... ince-2014/

India has set up rules to get around patent law but does import drugs that they can afford. It may have different safety and purity rules.
https://en.m.wikipedia.org/wiki/Central ... ganization

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Re: Drug manufacture

Post by Tero » Mon Jan 08, 2018 3:03 am

There are endless ”cheap drugs fromIndia” sites. They claim to sell you the drug directly and without Rx.

Mexico is similar. It could be a few are made there but some may come from Asia and have lower purity than US drugs
https://www.mexpro.com/blog/popular-rx- ... sed-mexico

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Re: Drug manufacture

Post by Tero » Mon Jan 08, 2018 4:11 am

Three of the top 5 are American.
https://blog.proclinical.com/who-are-th ... world-2017

I worked for an American company that still has a popular antihistamine on the market. It was swallowed up by what later became Sanofi, in 1996.

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Re: Drug manufacture

Post by Tero » Mon Jan 08, 2018 12:42 pm

Selling cheap in Europe:
The other point I keep making is that volume brings down cost. If you sell x tons in US you get a certain cost per pill. If you sell x tons in US and 2x in Europe and the rest of the world at say 5% profit over manufacture cost, your costs per ton will go down. They of course don’t lower the US cost, they just make more per pill or per Rx. There is a cut each time it is sold to thebpharmacy.

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Re: Drug manufacture

Post by Tero » Tue Jan 09, 2018 12:26 am

New secretary is Eli Lilly guy who is a pain in the penis.
https://www.politico.com/story/2018/01/ ... any-268942

They finagled 6 months more patent for cialis. For those not familiar with penile problems, you can have your erection up to 17h later whereas viagra you need to have a better plan of when the erection is needed. It lasts some hours, I think at least 3. I forget. See wikipedia.

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Re: Drug manufacture

Post by Tero » Tue Jan 09, 2018 1:49 am

More research than manufacture.

Pfizer admits defeat on Alzheimers and Parkinson’s. No drug in pipeline:
https://www.npr.org/sections/thetwo-way ... treatments

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Re: Drug manufacture

Post by JimC » Wed Jan 10, 2018 6:26 am

Breaking bad, Tero, breaking bad.

Just sayin'... :tea:
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And my gin!

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Re: Drug manufacture

Post by rainbow » Wed Jan 10, 2018 6:40 am

Äitisi nai poroja!

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Re: Drug manufacture

Post by Tero » Sun Feb 11, 2018 1:27 am


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Re: Drug manufacture

Post by Tero » Tue Feb 27, 2018 1:56 pm

Oxycontin was actually studied prior to launch, but here is a case where a controlled study on volunteers and actual pain patients, no more than a few thousand, failed to predict long term effects:
https://www.theguardian.com/music/2018/ ... -oxycontin

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Re: Drug manufacture

Post by pErvinalia » Tue Feb 27, 2018 2:06 pm

One tablet a day? Fucken lightweight! :crackpipesmiley:
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Re: Drug manufacture

Post by Tero » Tue Mar 06, 2018 5:18 pm

Opioids not effective for long term pain. Your brain just makes more receptors to dilute the effect:
https://www.npr.org/sections/health-sho ... ronic-pain

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Re: Drug manufacture

Post by Tero » Sun Jul 22, 2018 2:35 am

DEA sets quotas on opiates, by company. To cut down opiate abuse, quotas are down. Now hospitals are running out.
http://kios.org/post/doctors-raise-alar ... edications
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Re: Drug manufacture

Post by laklak » Sun Jul 22, 2018 3:15 am

Another stupid non-problem, the opioid "crisis". Who fucking cares? If you can't handle your drugs you OD, simple.
Yeah well that's just, like, your opinion, man.

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Re: Drug manufacture

Post by Tero » Sun Jul 22, 2018 12:52 pm

But they didn't know they were "drugs". They thought just, you know, drugs!
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